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Selective photochemical treatment of oestrogen receptor in a Xenopus liver extract destroys hormone binding and transcriptional activation but not DNA binding.

Photochemical excitation of a simple derivative of oestradiol using light in the UV-A range totally, permanently and selectively inactivates the oestrogen receptor protein present in a Xenopus liver extract without affecting its overall size. Inactivation of the binding site proceeds to completion w...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Cridland, N A, Wright, C V, McKenzie, E A, Knowland, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2347307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08311.x
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