Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases

BACKGROUND: There is limited data on the efficacy of anti-programmed death 1 (PD-1) antibodies in patients (pts) with melanoma brain metastasis (BM), particularly those which are symptomatic. METHOD: We retrospectively assessed pts with melanoma BM treated with PD-1 antibodies, nivolumab and pembrol...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Parakh, Sagun, Park, John J, Mendis, Shehara, Rai, Rajat, Xu, Wen, Lo, Serigne, Drummond, Martin, Rowe, Catherine, Wong, Annie, McArthur, Grant, Haydon, Andrew, Andrews, Miles C, Cebon, Jonathan, Guminski, Alex, Kefford, Richard F, Long, Georgina V, Menzies, Alexander M, Klein, Oliver, Carlino, Matteo S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518864/
https://ncbi.nlm.nih.gov/pubmed/28524161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.142
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