Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

The proto-oncogene c-kit encodes a transmembrane tyrosine protein kinase receptor for an unknown ligand and is allelic with the murine white-spotting locus (W). Mutations at the W locus affect various aspects of hematopoiesis, the proliferation and migration of primordial germ cells and melanoblasts...

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Bibliografiska uppgifter
Huvudupphovsmän: Nocka, K, Tan, J C, Chiu, E, Chu, T Y, Ray, P, Traktman, P, Besmer, P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC551885/
https://ncbi.nlm.nih.gov/pubmed/1693331
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