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Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming

BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in the regulation of systemic glucose homeostasi...

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Publicat a:Mol Metab
Autors principals: Guilherme, Adilson, Pedersen, David J., Henchey, Elizabeth, Henriques, Felipe S., Danai, Laura V., Shen, Yuefei, Yenilmez, Batuhan, Jung, DaeYoung, Kim, Jason K., Lodhi, Irfan J., Semenkovich, Clay F., Czech, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518709/
https://ncbi.nlm.nih.gov/pubmed/28752043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.012
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