Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

The human progesterone receptor (hPR) cDNA, synthesized from T47D breast cancer cells, and the hPR gene 5'-flanking region were cloned and sequenced. Comparison of the cDNA-deduced amino acid sequence with other PR homologues demonstrated the modular structure characteristic of nuclear receptors. As...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Kastner, P, Krust, A, Turcotte, B, Stropp, U, Tora, L, Gronemeyer, H, Chambon, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2328727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08280.x
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