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Cyclic hair-loss and regrowth in transgenic mice overexpressing an intermediate filament gene.

We have produced transgenic mice containing up to 250 copies of a sheep wool intermediate filament keratin gene to study the effect of its expression on hair structure and development. Several transgenic lines expressed the gene and in the one containing 250 transgenes, a pattern of hair-loss and re...

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Bibliographic Details
Main Authors: Powell, B C, Rogers, G E
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC551839/
https://ncbi.nlm.nih.gov/pubmed/1691707
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