Polyphenic trait promotes liver cancer in a model of epigenetic instability in mice

Hepatocellular carcinoma (HCC) represents the fifth‐most common form of cancer worldwide and carries a high mortality rate attributed to lack of effective treatment. Males are 8 times more likely to develop HCC than females, an effect largely driven by sex hormones, albeit through still poorly under...

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Dettagli Bibliografici
Pubblicato in:Hepatology
Autori principali: Cassano, Marco, Offner, Sandra, Planet, Evarist, Piersigilli, Alessandra, Jang, Suk Min, Henry, Hugues, Geuking, Markus B., Mooser, Catherine, McCoy, Kathy D., Macpherson, Andrew J., Trono, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518198/
https://ncbi.nlm.nih.gov/pubmed/28370258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29182
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