Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission‐VDAC1‐HK2‐mPTP‐mitophagy axis

The cardiac microvascular system, which is primarily composed of monolayer endothelial cells, is the site of blood supply and nutrient exchange to cardiomyocytes. However, microvascular ischemia/reperfusion injury (IRI) following percutaneous coronary intervention is a woefully neglected topic, and...

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Detalhes bibliográficos
Publicado no:J Pineal Res
Main Authors: Zhou, Hao, Zhang, Ying, Hu, Shunying, Shi, Chen, Zhu, Pingjun, Ma, Qiang, Jin, Qinhua, Cao, Feng, Tian, Feng, Chen, Yundai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518188/
https://ncbi.nlm.nih.gov/pubmed/28398674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12413
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