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Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by uncontrolled joint inflammation and destruction of bone and cartilage. We previously reported that C-X-C motif chemokine 10 (CXCL10; also called IP-10) has important roles in joint inflammation and bone destructio...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Lee, Jong-Ho, Kim, Bongjun, Jin, Won Jong, Kim, Hong-Hee, Ha, Hyunil, Lee, Zang Hee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518115/
https://ncbi.nlm.nih.gov/pubmed/28724396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1353-6
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