A Novel Role for RARα Agonists as Apolipoprotein CIII Inhibitors Identified from High Throughput Screening

Elevated triglyceride (TG) levels are well-correlated with the risk for cardiovascular disease (CVD). Apolipoprotein CIII (ApoC-III) is a key regulator of plasma TG levels through regulation of lipolysis and lipid synthesis. To identify novel regulators of TG levels, we carried out a high throughput...

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Publicado no:Sci Rep
Main Authors: Lee, Sang Jun, Mahankali, Madhupriya, Bitar, Abdallah, Zou, Huafei, Chao, Elizabeth, Nguyen, Hung, Gonzalez, Jose, Caballero, Dawna, Hull, Mitch, Wang, Danling, Schultz, Peter G., Shen, Weijun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517646/
https://ncbi.nlm.nih.gov/pubmed/28724938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05163-w
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