Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for future effective management of cancer. In this report, we show t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: AlShamaileh, Hadi, Wang, Tao, Xiang, Dongxi, Yin, Wang, Tran, Phuong Ha-Lien, Barrero, Roberto A., Zhang, Pei-Zhuo, Li, Yong, Kong, Lingxue, Liu, Ke, Zhou, Shu-Feng, Hou, Yingchun, Shigdar, Sarah, Duan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517644/
https://ncbi.nlm.nih.gov/pubmed/28724889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05859-z
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