Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for future effective management of cancer. In this report, we show t...

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Foilsithe in:Sci Rep
Main Authors: AlShamaileh, Hadi, Wang, Tao, Xiang, Dongxi, Yin, Wang, Tran, Phuong Ha-Lien, Barrero, Roberto A., Zhang, Pei-Zhuo, Li, Yong, Kong, Lingxue, Liu, Ke, Zhou, Shu-Feng, Hou, Yingchun, Shigdar, Sarah, Duan, Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517644/
https://ncbi.nlm.nih.gov/pubmed/28724889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05859-z
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