Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We therefore sought to identify transcriptional signatures in whole blood of Indian...

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Vydáno v:Sci Rep
Hlavní autoři: Gjøen, John Espen, Jenum, Synne, Sivakumaran, Dhanasekaran, Mukherjee, Aparna, Macaden, Ragini, Kabra, Sushil K., Lodha, Rakesh, Ottenhoff, Tom H. M., Haks, Marielle C., Doherty, Timothy Mark, Ritz, Christian, Grewal, Harleen M. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517635/
https://ncbi.nlm.nih.gov/pubmed/28724962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05057-x
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