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Physiological oxygen tension reduces hepatocyte dedifferentiation in in vitro culture
Primary hepatocytes cultured in vitro are a powerful tool to study the functions of hepatocytes and to evaluate the metabolism and toxicity of new drugs. However, in vitro culture of hepatocytes has proven to be very difficult. Ordinary culture conditions lead to dedifferentiation of hepatocytes, re...
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517567/ https://ncbi.nlm.nih.gov/pubmed/28724942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06433-3 |
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