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Opposite, bidirectional shifts in excitation and inhibition in specific types of dorsal horn interneurons are associated with spasticity and pain post-SCI

Spasticity, a common complication after spinal cord injury (SCI), is frequently accompanied by chronic pain. The physiological origin of this pain (critical to its treatment) remains unknown, although spastic motor dysfunction has been related to the hyperexcitability of motoneurons and to changes i...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Kopach, Olga, Medvediev, Volodymyr, Krotov, Volodymyr, Borisyuk, Anya, Tsymbaliuk, Vitaliy, Voitenko, Nana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517549/
https://ncbi.nlm.nih.gov/pubmed/28724992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06049-7
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