Transgenic Chickens Expressing the 3D8 Single Chain Variable Fragment Protein Suppress Avian Influenza Transmission

The 3D8 single chain variable fragment (scFv) is a mini-antibody that causes unusual sequence-independent nuclease activity against all types of nucleic acids. We used recombinant lentiviruses to generate transgenic chickens expressing the 3D8 scFv gene under the control of the chicken β-actin promo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: June Byun, Sung, Yuk, Seong-su, Jang, Ye-Jin, Choi, Hoonsung, Jeon, Mi-Hyang, Erdene-Ochir, TO, Kwon, Jung-Hoon, Noh, Jin-Yong, Sun Kim, Jeom, Gyu YOO, Jae, Song, Chang-Seon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517518/
https://ncbi.nlm.nih.gov/pubmed/28724948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05270-8
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