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Saturation mutagenesis of the DNA site bound by the small carboxy-terminal domain of gamma delta resolvase.

We have analyzed the sequence requirements for the binding of the carboxy-terminal (DNA binding) domain of gamma delta resolvase to its recognition site. Using an efficient procedure for saturation mutagenesis we have obtained 31 of the possible 36 base substitutions within the 12 bp minimal binding...

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Autori principali: Rimphanitchayakit, V, Grindley, N D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC551726/
https://ncbi.nlm.nih.gov/pubmed/2155779
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