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Reduced Frequency of Murine Cytomegalovirus Retinitis in C57BL/6 Mice Correlates with Low Levels of Suppressor of Cytokine Signaling (SOCS)1 and SOCS3 Expression within the Eye during Corticosteroid-Induced Immunosuppression

AIDS-related human cytomegalovirus retinitis remains a leading cause of blindness worldwide. We compared two C57BL/6 mouse models of experimental murine cytomegalovirus (MCMV) retinitis for intraocular expression of suppressors of cytokine signaling (SOCS)1 and SOCS3, host proteins that are inducibl...

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Bibliographic Details
Published in:Cytokine
Main Authors: Alston, Christine I., Dix, Richard D.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517024/
https://ncbi.nlm.nih.gov/pubmed/28558309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2017.05.021
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