Amino-terminal domain of NF1 binds to DNA as a dimer and activates adenovirus DNA replication.

NF1 is a DNA-binding protein involved in initiation of adenovirus DNA replication as well as in modulating the rate of transcription initiation of genes containing the sequence TGGCA. We show here that recombinant NF1 expressed via vaccinia virus is transported into the nucleus and binds to its cogn...

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Bibliographic Details
Main Authors: Gounari, F, De Francesco, R, Schmitt, J, van der Vliet, P, Cortese, R, Stunnenberg, H
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC551701/
https://ncbi.nlm.nih.gov/pubmed/2303041
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