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Immunologic response to vaccine challenge in pregnant PTPN22 R620W carriers and non-carriers

OBJECTIVES: Influenza infection is a significant cause of respiratory morbidity among pregnant women. Seasonal influenza vaccination engages innate immune receptors to promote protective immunity. A coding polymorphism (R620W) in PTPN22 imparts elevated risk for human infection and autoimmune diseas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tien, Shelly H., Crabtree, Juliet N., Gray, Heather L., Peterson, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517002/
https://ncbi.nlm.nih.gov/pubmed/28723925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181338
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