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A single DNA-binding transcription factor is sufficient for activation from a distant enhancer and/or from a promoter position.

Typical cell type-specific or inducible mammalian genes are under the control of one or more remote enhancers which transmit their effect to the promoter region located at the initiation site of transcription. Both enhancers and promoters are composed of multiple binding sites for transcription fact...

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Autors principals: Schatt, M D, Rusconi, S, Schaffner, W
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC551690/
https://ncbi.nlm.nih.gov/pubmed/2303037
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