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Transferrin-functionalized nanographene oxide for delivery of platinum complexes to enhance cancer-cell selectivity and apoptosis-inducing efficacy

Rational design and construction of delivery nanosystems for anticancer metal complexes is a crucial strategy to improve solubility under physiological conditions and permeability and retention behavior in tumor cells. Therefore, in this study, we designed and synthesize a transferrin (Tf)-conjugate...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhu, Hai, Zhou, Binwei, Chan, Leung, Du, Yanxin, Chen, Tianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516881/
https://ncbi.nlm.nih.gov/pubmed/28761342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S139207
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