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Sensitive detection of microRNAs based on the conversion of colorimetric assay into electrochemical analysis with duplex-specific nuclease-assisted signal amplification

miRNAs have emerged as new biomarkers for the detection of a wide variety of cancers. By employing duplex-specific nuclease for signal amplification and gold nanoparticles (AuNPs) as the carriers of detection probes, a novel electrochemical assay of miRNAs was performed. The method is based on conve...

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Publicat a:Int J Nanomedicine
Autors principals: Xia, Ning, Liu, Ke, Zhou, Yingying, Li, Yuanyuan, Yi, Xinyao
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516875/
https://ncbi.nlm.nih.gov/pubmed/28761341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S138656
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