Network reconstruction and validation of the Snf1/AMPK pathway in baker’s yeast based on a comprehensive literature review

BACKGROUND/OBJECTIVES: The SNF1/AMPK protein kinase has a central role in energy homeostasis in eukaryotic cells. It is activated by energy depletion and stimulates processes leading to the production of ATP while it downregulates ATP-consuming processes. The yeast SNF1 complex is best known for its...

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Gepubliceerd in:NPJ Syst Biol Appl
Hoofdauteurs: Lubitz, Timo, Welkenhuysen, Niek, Shashkova, Sviatlana, Bendrioua, Loubna, Hohmann, Stefan, Klipp, Edda, Krantz, Marcus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516868/
https://ncbi.nlm.nih.gov/pubmed/28725459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjsba.2015.7
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