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Post-transcriptional events are responsible for low expression of myelin basic protein in myelin deficient mice: role of natural antisense RNA.

Myelin deficient mice (mld) are characterized by tandem duplication of the gene coding for myelin basic protein (MBP). The upstream gene contains a large inversion of the 3' region which includes exons 3-7, and therefore it cannot give rise to mature mRNA and functional protein. MBP and MBP mRN...

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Bibliographic Details
Main Authors: Tosic, M, Roach, A, de Rivaz, J C, Dolivo, M, Matthieu, J M
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC551680/
https://ncbi.nlm.nih.gov/pubmed/1689239
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