Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin

Regulatory T cells (Tregs) are required to establish immune tolerance to commensal microbes. Tregs accumulate abruptly in the skin during a defined window of postnatal tissue development. However, the mechanisms mediating Treg migration to neonatal skin are unknown. Here we show that hair follicle (...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Scharschmidt, Tiffany C., Vasquez, Kimberly S., Pauli, Mariela L., Leitner, Elizabeth G., Chu, Kevin, Truong, Hong-An, Lowe, Margaret M., Rodriguez, Robert Sanchez, Ali, Niwa, Laszik, Zoltan G., Sonnenburg, Justin L., Millar, Sarah E., Rosenblum, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516645/
https://ncbi.nlm.nih.gov/pubmed/28343820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.03.001
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