Mitochondrial respiratory inhibition by N-methylated beta-carboline derivatives structurally resembling N-methyl-4-phenylpyridine.

Mitochondrial accumulation and respiratory inhibition are critical steps in the actions of N-methyl-4-phenylpyridinium ion (MPP+), the toxic metabolite of the parkinsonism-inducing agent, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. We examined the respiratory characteristics of 2-methylated beta-c...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Albores, R, Neafsey, E J, Drucker, G, Fields, J Z, Collins, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9368
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!