Arcyriaflavin a, a cyclin D1–cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis

BACKGROUND: We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to evaluate the potential therapeutic effects of cyclin D1 inhibitors in endometriot...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Hirakawa, Tomoko, Nasu, Kaei, Aoyagi, Yoko, Takebayashi, Kanetoshi, Narahara, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516342/
https://ncbi.nlm.nih.gov/pubmed/28720098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-017-0272-3
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