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The mannose 6-phosphate receptor cytoplasmic domain is not sufficient to alter the cellular distribution of a chimeric EGF receptor.

Unlike most receptors, 300 kd mannose 6-phosphate receptors (MPRs) are localized primarily in the trans-Golgi network (TGN) and endosomes, and they cycle constitutively between these compartments. Yet, when present at the cell surface, MPRs are internalized together with other cell surface receptors...

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Udgivet i:EMBO J
Principais autores: Dintzis, S M, Pfeffer, S R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08082.x
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