Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

Excess collagen synthesis (fibrogenesis) in the liver plays a causal role in the progression of nonalcoholic fatty liver disease (NAFLD). Methods are needed to identify patients with more rapidly progressing disease and to demonstrate early response to treatment. We describe here a novel method to q...

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Vydáno v:Hepatology
Hlavní autoři: Decaris, Martin L., Li, Kelvin W., Emson, Claire L., Gatmaitan, Michelle, Liu, Shanshan, Wang, Yenny, Nyangau, Edna, Colangelo, Marc, Angel, Thomas E., Beysen, Carine, Cui, Jeffrey, Hernandez, Carolyn, Lazaro, Len, Brenner, David A., Turner, Scott M., Hellerstein, Marc K., Loomba, Rohit
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Steatohepatitis/Metabolic Liver Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516243/
https://ncbi.nlm.nih.gov/pubmed/27706836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28860
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