Blockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer

Axl receptor tyrosine kinase is involved in the tumorigenesis and metastasis of many cancers. Axl expression was markedly higher in human papilloma virus type 16E6 (HPV16E6)-overexpressing HeLa (HE6F) cells and lower in HPV16E6-suppressing CaSki (CE6R) cells than in the controls. SiRNA-mediated knoc...

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Publicat a:Sci Rep
Autors principals: Lee, Eun-Hee, Ji, Kon-Young, Kim, Eun-Mi, Kim, Su-Man, Song, Hyeong-Woo, Choi, Ha-Rim, Chung, Byung Yeoup, Choi, Hyo Jin, Bai, Hyoung-Woo, Kang, Hyung-Sik
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516033/
https://ncbi.nlm.nih.gov/pubmed/28720772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05977-8
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