A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

Doxorubicin forms the basis of chemotherapy regimens for several malignancies, including triple negative breast cancer (TNBC). Here, we present a coupled experimental/modeling approach to establish an in vitro pharmacokinetic/pharmacodynamic model to describe how the concentration and duration of do...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: McKenna, Matthew T., Weis, Jared A., Barnes, Stephanie L., Tyson, Darren R., Miga, Michael I., Quaranta, Vito, Yankeelov, Thomas E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516013/
https://ncbi.nlm.nih.gov/pubmed/28720897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05902-z
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