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Dysregulated miRNAs and their pathogenic implications for the neurometabolic disease propionic acidemia

miRNome expression profiling was performed in a mouse model of propionic acidemia (PA) and in patients’ plasma samples to investigate the role of miRNAs in the pathophysiology of the disease and to identify novel biomarkers and therapeutic targets. PA is a potentially lethal neurometabolic disease w...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Rivera-Barahona, Ana, Fulgencio-Covián, Alejandro, Pérez-Cerdá, Celia, Ramos, Ricardo, Barry, Michael A., Ugarte, Magdalena, Pérez, Belén, Richard, Eva, Desviat, Lourdes R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516006/
https://ncbi.nlm.nih.gov/pubmed/28720782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06420-8
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