Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with genetic and clinical heterogeneity. The interplay of de novo and inherited rare variants has been suspected in the development of ASD. Here, we applied whole exome sequencing (WES) on 19 trios from singleton Saudi families...

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Pubblicato in:Sci Rep
Autori principali: Al-Mubarak, Bashayer, Abouelhoda, Mohamed, Omar, Aisha, AlDhalaan, Hesham, Aldosari, Mohammed, Nester, Michael, Alshamrani, Hussain. A., El-Kalioby, Mohamed, Goljan, Ewa, Albar, Renad, Subhani, Shazia, Tahir, Asma, Asfahani, Sultana, Eskandrani, Alaa, Almusaiab, Ahmed, Magrashi, Amna, Shinwari, Jameela, Monies, Dorota, Al Tassan, Nada
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515956/
https://ncbi.nlm.nih.gov/pubmed/28720891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06033-1
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