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Effect of head group and lipid tail oxidation in the cell membrane revealed through integrated simulations and experiments

We report on multi-level atomistic simulations for the interaction of reactive oxygen species (ROS) with the head groups of the phospholipid bilayer, and the subsequent effect of head group and lipid tail oxidation on the structural and dynamic properties of the cell membrane. Our simulations are va...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yusupov, M., Wende, K., Kupsch, S., Neyts, E. C., Reuter, S., Bogaerts, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515852/
https://ncbi.nlm.nih.gov/pubmed/28720839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06412-8
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