Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer

This study explored decreased tumor suppressor microRNA (miRNA) plasma levels in pancreatic cancer (PCa) patients to clarify their potential as novel biomarkers and therapeutic targets. We used the microRNA array-based approach to select candidates by comparing plasma levels between PCa patients and...

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Udgivet i:Sci Rep
Main Authors: Imamura, Taisuke, Komatsu, Shuhei, Ichikawa, Daisuke, Miyamae, Mahito, Okajima, Wataru, Ohashi, Takuma, Kiuchi, Jun, Nishibeppu, Keiji, Konishi, Hirotaka, Shiozaki, Atsushi, Morimura, Ryo, Ikoma, Hisashi, Ochiai, Toshiya, Okamoto, Kazuma, Taniguchi, Hiroki, Otsuji, Eigo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515843/
https://ncbi.nlm.nih.gov/pubmed/28720759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06137-8
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