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Evidence against a requisite role for defective virus in the establishment of persistent hepadnavirus infections.

The factors involved in the establishment of persistent hepadnavirus infection are poorly understood. Recent findings demonstrate that the sequence of the genome of hepatitis B virus (HBV) is variable in infected individuals and that, in some cases, virus mutants predominate. Our objectives in the p...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Miller, R H, Girones, R, Cote, P J, Hornbuckle, W E, Chestnut, T, Baldwin, B H, Korba, B E, Tennant, B C, Gerin, J L, Purcell, R H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55158/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9329
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