V(D)J recombination activity in lymphoid cell lines is increased by agents that elevate cAMP.
V(D)J [variable--(diversity)--joining] recombination is regulated developmentally, being restricted to cells of the early B- and T-lymphocyte lineages. In this report we show that recombination activity can also be regulated in response to chemical effectors. Compounds that increase intracellular cA...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1701258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9324 |
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