Spaceflight-induced vertebral bone loss in ovariectomized rats is associated with increased bone marrow adiposity and no change in bone formation

There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast differentiation. MAT is increased in rodents during spaceflight but a causal relationship between MAT and bone loss remains unclear. In the pres...

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Vydáno v:NPJ Microgravity
Hlavní autoři: Keune, Jessica A, Philbrick, Kenneth A, Branscum, Adam J, Iwaniec, Urszula T, Turner, Russell T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515514/
https://ncbi.nlm.nih.gov/pubmed/28725730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjmgrav.2016.16
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