Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells

The epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells plays a central role in the development of proliferative vitreoretinopathy (PVR). The purpose of this study was to investigate the effect of AMP-activated protein kinase (AMPK), a key regulator of energy homeostasi...

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Vydáno v:PLoS One
Hlavní autoři: Matoba, Ryo, Morizane, Yuki, Shiode, Yusuke, Hirano, Masayuki, Doi, Shinichiro, Toshima, Shinji, Araki, Ryoichi, Hosogi, Mika, Yonezawa, Tomoko, Shiraga, Fumio
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515442/
https://ncbi.nlm.nih.gov/pubmed/28719670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181481
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