RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells

G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling cascade. The second mechanism is via the utilization of the β-arrestin signalling molecule and thirdly vi...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kamato, Danielle, Bhaskarala, Venkata Vijayanand, Mantri, Nitin, Oh, Tae Gyu, Ling, Dora, Janke, Reearna, Zheng, Wenhua, Little, Peter J, Osman, Narin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515425/
https://ncbi.nlm.nih.gov/pubmed/28719611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180842
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