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TNF is a key cytokine mediating neutrophil cytotoxic activity in breast cancer patients

We have previously shown a novel antimetastatic role for neutrophils in the premetastatic lung of mice in models of breast cancer. Here we expand on those findings in the context of human breast cancer. We assessed the cytotoxicity of neutrophils from 90 newly diagnosed breast cancer patients, 24 du...

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Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Principais autores: Comen, Elizabeth, Wojnarowicz, Paulina, Seshan, Venkatraman E, Shah, Riddhi, Coker, Courtney, Norton, Larry, Benezra, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515342/
https://ncbi.nlm.nih.gov/pubmed/28721376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbcancer.2016.9
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