Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

Pathological analysis of the nuclear proliferation biomarker Ki67 has multiple potential roles in breast and other cancers. However, clinical utility of the immunohistochemical (IHC) assay for Ki67 immunohistochemistry has been hampered by unacceptable between-laboratory analytical variability. The...

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Published in:NPJ Breast Cancer
Main Authors: Leung, Samuel C Y, Nielsen, Torsten O, Zabaglo, Lila, Arun, Indu, Badve, Sunil S, Bane, Anita L, Bartlett, John M S, Borgquist, Signe, Chang, Martin C, Dodson, Andrew, Enos, Rebecca A, Fineberg, Susan, Focke, Cornelia M, Gao, Dongxia, Gown, Allen M, Grabau, Dorthe, Gutierrez, Carolina, Hugh, Judith C, Kos, Zuzana, Lænkholm, Anne-Vibeke, Lin, Ming-Gang, Mastropasqua, Mauro G, Moriya, Takuya, Nofech-Mozes, Sharon, Osborne, C Kent, Penault-Llorca, Frédérique M, Piper, Tammy, Sakatani, Takashi, Salgado, Roberto, Starczynski, Jane, Viale, Giuseppe, Hayes, Daniel F, McShane, Lisa M, Dowsett, Mitch
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515324/
https://ncbi.nlm.nih.gov/pubmed/28721378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbcancer.2016.14
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