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Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.

Transcriptional activation by steroid hormones is often associated with the appearance of a DNase I hypersensitive site resulting from a local alteration of the nucleoprotein structure of the promoter. For the mouse mammary tumor virus long terminal repeat, a viral promoter under glucocorticoid cont...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Carr, K D, Richard-Foy, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1979170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9300
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