Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a Chilean population

Inter-individual differences in arsenic metabolism have been linked to arsenic-related disease risks. Arsenic (+3) methyltransferase (AS3MT) is the primary enzyme involved in arsenic metabolism, and we previously demonstrated in vitro that N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) also m...

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Dettagli Bibliografici
Pubblicato in:Environ Mol Mutagen
Autori principali: de la Rosa, Rosemarie, Steinmaus, Craig, Akers, Nicholas K, Conde, Lucia, Ferreccio, Catterina, Kalman, David, Zhang, Kevin R, Skibola, Christine F, Smith, Allan H, Zhang, Luoping, Smith, Martyn T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515250/
https://ncbi.nlm.nih.gov/pubmed/28640505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22104
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