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THE INTRAGRAFT MICROENVIRONMENT AS A CENTRAL DETERMINANT OF CHRONIC REJECTION OR LOCAL IMMUNOREGULATION/ TOLERANCE

PURPOSE OF REVIEW: Chronic rejection is associated with persistent mononuclear cell recruitment, endothelial activation and proliferation, local tissue hypoxia and related biology that enhance effector immune responses. Despite similarities, the tumor microenvironment elicits signals/factors that in...

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Dettagli Bibliografici
Pubblicato in:Curr Opin Organ Transplant
Autori principali: Wedel, Johannes, Nakayama, Hironao, Kochupurakkal, Nora M., Koch, Josephine, Klagsbrun, Michael, Bielenberg, Diane R., Briscoe, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515240/
https://ncbi.nlm.nih.gov/pubmed/27898465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000373
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