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Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling

BACKGROUND: Dishevelled (Dsh) is a key component of multiple signaling pathways that are initiated by Wnt secreted ligands and Frizzled receptors during embryonic development. Although Dsh has been detected in a number of cellular compartments, the importance of its subcellular distribution for sign...

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Autors principals: Itoh, Keiji, Brott, Barbara K, Bae, Gyu-Un, Ratcliffe, Marianne J, Sokol, Sergei Y
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC551520/
https://ncbi.nlm.nih.gov/pubmed/15720724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol20
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