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CCR7/p-ERK1/2/VEGF signaling promotes retinal neovascularization in a mouse model of oxygen-induced retinopathy

AIM: To investigate the role of CCR7/p-ERK1/2/VEGF signaling in the mouse model of oxygen-induced retinopathy (OIR). METHODS: Neonatal C57BL/6J mice were evenly randomized into four groups: normoxia, OIR, OIR control (treated with scramble siRNA), and OIR treated (treated with CCR7 siRNA). Normoxia...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Yuan, Lin-Hui, Chen, Xiao-Long, Di, Yu, Liu, Mei-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515149/
https://ncbi.nlm.nih.gov/pubmed/28730075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2017.06.06
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