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TraR directly regulates transcription initiation by mimicking the combined effects of the global regulators DksA and ppGpp

The Escherichia coli F element-encoded protein TraR is a distant homolog of the chromosome-encoded transcription factor DksA. Here we address the mechanism by which TraR acts as a global regulator, inhibiting some promoters and activating others. We show that TraR regulates transcription directly in...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Gopalkrishnan, Saumya, Ross, Wilma, Chen, Albert Y., Gourse, Richard L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514744/
https://ncbi.nlm.nih.gov/pubmed/28652326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704105114
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