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Mouse models of UV-induced melanoma: genetics, pathology, and clinical relevance

Melanocytes, a neural crest cell derivative, produce pigment to protect keratinocytes from ultraviolet radiation (UVR). Although melanocytic lesions such as nevi and cutaneous malignant melanomas are known to be associated with sun exposure, the role of UVR in oncogenesis is complex and has yet to b...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Day, Chi-Ping, Marchalik, Rachel, Merlino, Glenn, Michael, Helen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514606/
https://ncbi.nlm.nih.gov/pubmed/28092363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.155
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