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Mouse models of UV-induced melanoma: genetics, pathology, and clinical relevance
Melanocytes, a neural crest cell derivative, produce pigment to protect keratinocytes from ultraviolet radiation (UVR). Although melanocytic lesions such as nevi and cutaneous malignant melanomas are known to be associated with sun exposure, the role of UVR in oncogenesis is complex and has yet to b...
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Publicado no: | Lab Invest |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514606/ https://ncbi.nlm.nih.gov/pubmed/28092363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.155 |
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