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The x-ray crystal structure of the keratin 1–keratin 10 helix 2B heterodimer reveals molecular surface properties and biochemical insights into human skin disease
Keratins 1 (K1) and 10 (K10) are the primary keratins expressed in differentiated epidermis. Mutations in K1/K10 are associated with human skin diseases. We determined the crystal structure of the complex between the distal (2B) helices of K1 and K10 to better understand how human keratin structure...
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| Publicado no: | J Invest Dermatol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514376/ https://ncbi.nlm.nih.gov/pubmed/27595935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.08.018 |
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